Medical Risk factors for dementia; A case-control study

Authors

  • Ahmadali Akbari Kamrani Associate Professor Department of Ageing, Research Center on Ageing, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
  • Fatemeh Nourhashemi Gérontopole, Toulouse University Hospital, 20 rue du pont Saint Pierre, 31059 Toulouse - France
  • hossein Ghasemzadeh Department of Ageing, Research Center on Ageing, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
  • Robab Sahaf associate professor, Department of Ageing, Research Center on Ageing, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
  • Yadollah Abolfathi Momtaz assistant Professor Department of Ageing, Research Center on Ageing, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Abstract:

Introduction: Dementia, the fifth cause of death in older adults with the most significant financial, social and caring burden on health systems across the world. Aim: to determine the most common medical risk factors for dementia in the retired population. Methods: A case-control methodology was utilized for this study, within which 180 established dementia patients compared to 371 controls for medical risk factors in NIOC in 2017. Participants in two Cases and control groups were matched for age, educational level, and sex. The logistic regression was employed to estimate odds ratios using SPSS statistical software. Results: The majority of the participants were male (55%) and married (69%) with a mean age (SD) of 73.14(9.11) and high-school education (38%). The results of the adjusted logistic regression showed a significant association between dementia and chronic and acute vitamin D3 deficiency (more than and less than one year) (OR=4.73, P<0.001, OR=7.50, P<0.001, respectively), cancer history (OR=15.31, P<0.001), and chronic anemia (OR=5.95, P<0.001). Conclusion: The results of this study suggest vitamin D3 deficiency, cancer, and anemia history as probable risk factors for dementia. Thus, managing or controlling these risk factors may effectively delay or prevent the onset of dementia for the individuals

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volume 17  issue 4

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publication date 2019-12

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